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There are several basic science studies that aim to investig
2022-02-18
There are several basic science studies that aim to investigate potential mechanisms behind the reduced incidence of MI in factor Xa inhibitor treated patients. Perzborn et al. reported that in-vitro addition of rivaroxaban reduced tissue-factor induced platelet aggregation (Perzborn, Heitmeier, & L
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It is interesting that SEC significantly inhibited
2022-02-17
It is interesting that SEC significantly inhibited cell migration and EMT in PC3 cells expressing a low RKIP level and HEK293T RKIP−/− cells, while had no effect on HEK293T RKIP+/+ cells. These observations can be interpreted that the RKIP-ANXA7 association may block SEC-induced ANXA7 GTPase activat
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br GPR is a class
2022-02-17
GPR119 is a class A GPCR expressed on pancreatic β-cells and certain enteroendocrine sphingosine 1-phosphate receptor modulator which upon activation with an agonist, increases insulin secretion in response to rising glucose levels. Mechanistically, this insulinotropic effect is bifurcated involvi
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Wasting syndrome is a common complication of HIV infection a
2022-02-17
Wasting syndrome is a common complication of HIV infection and is marked by progressive weight loss and weakness, often associated with fever (Weinroth et al., 1995). Fever is a highly complex process initiated by the action on the Adapalene thermosensitive cells of a number of endogenous pyrogens,
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We tested this hypothesis with two
2022-02-17
We tested this hypothesis with two experiments. In the first experiment OVX monkeys implanted with an E2 Ampicillin Trihydrate synthesis (this results in LH levels similar to the level during the follicular phase) were treated with daily injections of letrozole for 1 week and then EB was injected s
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br Conclusion br Acknowledgments br Introduction The gyloxal
2022-02-17
Conclusion Acknowledgments Introduction The gyloxalase pathway is a well-conserved antioxidant defense system found in all cells of the body [1], [2], [3], [4]. The glyoxalase pathway facilitates the neutralization of highly reactive and oxidizing dicarbonyl molecules, with methylglyoxal (M
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br WM astrocytes Grey matter astrocytes express a variety of
2022-02-17
WM astrocytes Grey matter astrocytes express a variety of GluR types that have both physiological and pathophysiological significance [87]. Non-NMDA GluR are also expressed in WM astrocytes [40], although the functionality of these receptors has not been tested. The fibrous astrocytes that popula
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ap1 Boswellia papyrifera Del Hochst mostly grows in Sudanian
2022-02-17
Boswellia papyrifera (Del.) Hochst., mostly grows in Sudanian and Sahelian regions and their oleo-gum resin is used medically in treatment of rheumatism, menorrhagia, amenorrhoea, vaginal infections, ulcers, sores, polyuria, syphilis, bronchitis, scrofulous affections, inflammations, asthma, diarrhe
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br Acknowledgments This research was supported by a grant
2022-02-17
Acknowledgments This research was supported by a grant from the Korea Health Technology R&D Project through the Korean Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI17C0616). Dr. Jun-Mo Yang was supported by the Natio
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br Materials and methods br
2022-02-17
Materials and methods Results Discussion Acknowledgments This work was financially supported by the University of Tehran, Iran. The authors thank all the teams who worked on the experiments and who provided technical assistance in the laboratory during this study. We also thank the anony
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The absence of differences between GalR knockout and wild
2022-02-17
The absence of differences between GalR1 knockout and wild type mice in kainic acid-induced seizures suggests that GalR1 do not interfere with the seizure-inducing action of kainic acid. Postsynaptic kainate receptors are excitatory ionotropic glutamate receptors and their activation leads to seizur
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Furthermore our results are the
2022-02-17
Furthermore, our results are the first to demonstrate that the stimulating effect of GALP on AVP release in rats is independent of galanin receptors. The same stimulatory GALP influence on AVP secretion has been also observed in the presence of galantide, an antagonist of Gal receptors in the incuba
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Macroautophagy hereafter referred to as autophagy
2022-02-16
Macroautophagy (hereafter referred to as autophagy) depends on an intracellular lysosome-dependent degradation system that maintains cellular metabolism and homeostasis [11]. Genes involved in these processes are termed autophagy-related genes (ATGs), which regulate autophagosome formation and comp
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br Acknowledgements The authors have no
2022-02-16
Acknowledgements The authors have no ethical conflicts to disclose. The authors have no conflicts of interest to declare. This work was funded by the Research Council of Lithuania. Introduction This paper studies whether there is a causal influence of the risk-taking incentives provided by op
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The stud http www apexbt com media diy images wb
2022-02-16
The study was supported by Science Foundation for the Youth Scholars of Hubei Provincial Department of Education for Science and technology research program (No.: Q2017007). Introduction Chlorpyrifos is an organophosphate (OP) insecticide widely used in a variety of food crops to control a great
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