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br ARIs in the prevention of prostate cancer Prostate cancer
2023-10-20
5ARIs in the prevention of prostate cancer Prostate cancer continues to be a leading cause of male deaths worldwide. In 2009, it was estimated there would be 192,280 new cases of prostate cancer with a predicted 27,360 deaths [25]. Because androgens, and specifically DHT, play a large role in bot
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k145 br Diabetes and obesity fit or fat sugar or not
2023-10-20
Diabetes and obesity: fit or fat; sugar or not: the autophagic verdict Type 2 diabetes and obesity are among the most emerging health problems worldwide. The factors that are responsible for the establishment of diabetes include decreased k145 production, rise in adiposity, and an increase in ins
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bts products In this study we observed the ATPase
2023-10-20
In this study, we observed the ATPase activity of RaGroEL at various temperatures and metal ions conditions and the role of GroES in the ATPase activity of RaGroEL. Furthermore, we quantified the expression of groEL genes under different abiotic stresses, including temperature, pH, salt and oxygen s
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Protein phosphorylation is an important
2023-10-20
Protein phosphorylation is an important posttranslational mechanism for the regulation of distribution, trafficking, and function of modified proteins (Wang et al., 2014). GluA1 phosphorylation at S845 also has functional consequences (Lu and Roche, 2012). For instance, S845 phosphorylation drove tr
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The following are the supplementary data related to
2023-10-20
The following are the supplementary data related to this article. Competing interest Ethics approval and consent to participate Authors' contributions Acknowledgements The authors thank Dr. D. R. Kaplan for kind advice and materials derived from NB primary cell lines, Dr. F. D. Miller f
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Another heroic set of studies combining retrodialysis with
2023-10-20
Another heroic set of studies combining retrodialysis with electrophysiological recording at two distinct brain sites further indicated that the estradiol-induced increase in auditory-evoked firing in NCM also enhanced the selectivity of auditory-evoked responses in the downstream sensorimotor nucle
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Since the beginning of s more
2023-10-20
Since the beginning of 1990s, more than 17,000 papers about physiological relevance of antioxidants have been published according to data from web of science. Based on the available literature, it seems that assessing the antioxidant potential of food by means of in vitro assays or solely epidemiolo
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It was deduced empirically that
2023-10-20
It was deduced empirically that the helix direction of the COOC torsion might relate to the sign of the peroxide Cotton effect. Huang reported ab initio calculation of the peroxide bond using MRDCI method and DZP basis set, but only the fragment CH3OOCH3 instead of full molecule was studied [19]. Si
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Another hypothesis is angiogenesis inhibition Angiogenesis i
2023-10-20
Another hypothesis is angiogenesis inhibition. Angiogenesis is a process that involves the growth, migration and differentiation of endothelial 74 9 to form new blood vessels. Angiogenesis favorably influences tumor growth and also influences tumor invasion of vessels, resulting in tumor metastasis.
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At the organismal level skeletal muscle lung
2023-10-19
At the organismal level, skeletal muscle, lung and adipose tissues mediate net de novo synthesis and release of glutamine, whereas net glutamine catabolism occurs in the kidney [7]. The liver exhibits net glutamine consumption coupled to urea production in the post-absorptive state, and net glutamin
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In addition to it we also showed that glycine
2023-10-19
In addition to it, we also showed that glycine increases miR-301a expression which directly binds to PTEN 3′UTR target sites [13]. Glycine confers neuroprotection through microRNA-301a/PTEN signaling in rats cortical neurons in oxygen deprivation model [13]. Substantial studies indicate that inhibit
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br ABCA mRNA expression is elevated
2023-10-19
ABCA2 mRNA expression is elevated in Niemann-Pick type C and familial hypercholesterolemia fibroblasts Niemann-Pick Type C disease is a neurological disorder of adolescents due to autosomal-recessive mutations in either one or both Niemann-Pick-2 (NPC2) and NPC1 genes, which, like ABCA2, are loca
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br Expression of adiponectin mRNA in chickens We first sough
2023-10-19
Expression of adiponectin mRNA in chickens We first sought to determine the nucleotide sequence of the chicken adiponectin cDNA. The open reading frame of the chicken adiponectin cDNA consists of 735 nucleotides that was 65–68% homologous to various mammalian adiponectin cDNAs (Maddineni et al.,
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In another study authors found that ADORA
2023-10-19
In another study, authors found that ADORA1 were present on the intrinsically photosensitive retinal ganglion sn-Glycero-3-phosphocholine mg (ipRGCs), and application of adenosine to rat retinas reduced light-evoked spiking of ipRGCs through suppression of a cAMP-mediated pathway (Sodhi and Hartwick
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It is well accepted that PKA is a key enzyme
2023-10-19
It is well accepted that PKA is a key enzyme activated at the beginning of the capacitation process [69]. As mentioned above phosphorylation/inactivation of cofilin in sperm is a PKA dependent process [58]. We could not see any change in cofilin phosphorylation level by adding the PKA activator 8Br-
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