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br Experimental Procedures A detailed version of our Experim
2018-10-31
Experimental Procedures A detailed version of our Experimental Procedures can be found in the Supplemental Experimental Procedures. All animal experiments were approved by the Danish Council for Supervision with Experimental Animals (#2011/561-1966). AR was performed at P1 as previously described
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EPI-001 We further show that Zfp iNSCs lines established fro
2018-10-31
We further show that Zfp521-iNSCs lines established from fetal, neonatal, and adult fibroblasts have the capacity to differentiate in vitro into the three main cell types: neurons, astrocytes and oligodendrocytes. This trilineage differentiation potential was also retained in three clonally derived
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Childhood socioeconomic status SES has been repeatedly ident
2018-10-30
Childhood socioeconomic status (SES) has been repeatedly identified as a risk factor for adolescent and young adult mental health (Pascoe et al., 2016). Low SES during childhood may increase children and adolescents’ exposure and vulnerability to stressors including daily hassles, traumatic events,
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br Acknowledgements br Introduction Japan is
2018-10-30
Acknowledgements Introduction Japan is widely perceived as a country with a low level of HIV occurrence (Suguimoto et al., 2014; Koerner & Ichikawa, 2011; Kihara & Komatsu, 2003; Wada, Funada & Shimane, 2013). Surveillance data present in Japanese government reports support this perception (Mi
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br Distinguishing features of and selected tensions
2018-10-30
Distinguishing features of, and selected tensions within, a model-based perspective A model-based perspective emphasizes the processes producing outcome variation, and observed data are used to characterize that data-generating process. This is the majority perspective in statistical textbooks, i
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Although both men and women in these
2018-10-30
Although both men and women in these types of jobs face similar hazards, women are likely to have higher levels of mobility limitations than men, even controlling for the effects of age. These sex differentials may be due, in part, to selection of men and women into these job categories, differences
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br Materials and methods br Results br Discussion In SPR
2018-10-30
Materials and methods Results Discussion In SPR studies, the binding of vancomycin to the control surfaces was much weaker than that to doc-KAA surfaces, consistent with previous observations that vancomycin specifically binds to the bacterial cell wall precursor lipid II, rather than to ph
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br Geometries of proposed O PCF
2018-10-30
Geometries of proposed O-PCF The cross sectional views of the proposed O-PCF, S-PCF and H-PCF have been shown in Fig. 1. The figure clearly depicts the whole geometrical structure of the PCF. The proposed structures of the PCF are in square, hexagonal and octagonal shapes. So the vertices of the
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Lo anterior nos indica que
2018-10-30
Lo anterior nos indica que los comportamientos en materia de crecimiento económico han sido diferenciales, al igual que los de población, pues el per cápita es igual al /población, viéndose afectado por las dos variables y puede dar lugar hordenine dissolve solubility múltiples combinaciones. Sin e
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br Comentarios finales Ucrania ha vivido peores adversidades
2018-10-30
Comentarios finales Ucrania ha vivido peores adversidades que países como México o Estados Unidos y no ha tenido la atención que debería; en estas naciones las contracciones en el producto durante las crisis más severas no se comparan con lo que ha experimentado Ucrania. Cuando México sufrió la c
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br II Los aspectos energ ticos
2018-10-30
II. Los aspectos energéticos En términos generales la ue depende mucho del exterior para suplir su demanda energética, tan solo durante 2013 el 53% de los combustibles que consumió llegaron de países externos al bloque y a pesar de que ha implementado varias acciones en amparo de su seguridad ene
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MtDNA is usually present in multiple identical
2018-10-30
MtDNA is usually present in multiple identical copies in the cells, but the location of MtDNA close to the electron transport chain renders it more susceptible to ROS induced damage and mutations. In diabetes patients, MtDNA may be exposed to hyperglycaemia induced oxidative stress (Singh et al., 20
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This interpretation is consistent with results from animal
2018-10-30
This interpretation is consistent with results from animal studies. In mice, as in humans, enhanced systemic inflammation is associated with accelerated ageing and increased mortality risk (Osorio et al., 2012; Kawahara et al., 2009; Tilstra et al., 2012; Caballero et al., 2009). Importantly, system
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br Acknowledgments br Introduction Sickle cell disease
2018-10-30
Acknowledgments Introduction Sickle cell disease (SCD) is one of the commonest severe inherited disorders affecting millions of people worldwide (Piel et al., 2013). Complications of the disease arise from the presence in patients\' red cells of the abnormal haemoglobin (Hb), HbS, which has a
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The response to self or non
2018-10-30
The response to (self or non-self) ldv cost restricted by similar class II MHC molecules leads to a usage of a limited number of rearrangements of the Beta chain of the TCR, shared among several patients, with common variable-diversity-junctional segments (V-D-J) and similar three-dimensional struc
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