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In contrast to the RRP the abdominal cavity was not
2018-11-06
In Wnt-C59 to the RRP, the abdominal cavity was not entered in a radical perineal prostatectomy (RPP), so it seems reasonable to assume that the risk of developing an IH postoperatively would not be increased. In the series of Matsubara et al, the incidence of IHs after an RPP was 1.8% (5 of 285) w
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br Introduction Spinal hematoma is a
2018-11-06
Introduction Spinal hematoma is a rare disease entity. In the literature review and meta-analysis of 613 patients presenting with spinal hematoma reported by Kreppel et al, isolated spinal subdural hematoma (SSDH) comprised only 4.1% of all spinal hematomas. Case reports Discussion SSDH is
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br Discussion TTE was first described
2018-11-06
Discussion TTE was first described by Von Lenhossek in 1886 in an autopsy case; since then, >100 cases have been reported. Familial occurrences have been reported, and most were associated with persistent Müllerian duct syndrome. Typically, patients present with uniform symptoms of an inguinal he
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br Case Report Physical examination revealed
2018-11-06
Case Report Physical examination revealed normal response in the patient\'s upper limbs and normal vital signs. Blood test results indicated no abnormalities; however, spinal MRI revealed an epidural mass lesion (10 mm × 12 mm × 63 mm) in the posterior epidural space from T9 to T11 in the spinal
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br Introduction Cecal volvulus is a rare condition in the
2018-11-06
Introduction Cecal volvulus is a rare condition in the pediatric population. Cecal bascule, a variant of cecal volvulus, is a condition in which the cecum anteriorly folds over the ascending colon, leading to large bowel obstruction. Cecal bascule is also rare, with only a few cases reported in t
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Oxidative stress status occurs when ROS accumulate Superoxid
2018-11-06
Oxidative stress status occurs when ROS accumulate. Superoxide dismutases (SOD), one of antioxidant enzymes, catalyzes the dismutation of superoxide anion () into O2 and hydrogen peroxide (H2O2). Subsequently, H2O2 is reduced to H2O by glutathione peroxidase (GSH-Px) in the cytosol, or by catalase (
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Spontaneous differentiation of hESCs into different
2018-11-06
Spontaneous differentiation of hESCs into different cell types can be triggered by formation of 3-dimensional (3D) embryoid bodies (EBs) (Itskovitz-Eldor et al., 2000). Although the EB is far less organized than an embryo, it can partially mimic the spatial organization of rock pathway in an embryo
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Epigenetic modifications DNA methylation in particular
2018-11-06
Epigenetic modifications, DNA methylation in particular, regulate key developmental processes including germ cell imprinting and stem cell maintenance/differentiation and play a crucial role in the early periods of embryogenesis (Bartolomei, 2003; Kiefer, 2007; Kondo, 2006; Surani et al., 2007). DNA
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br Materials and methods br Results br Discussion
2018-11-06
Materials and methods Results Discussion Strategies aiming at controlled divergence of ASCs to specific differentiated cell types essentially rely on prolonged culture in the presence of specific sets of growth factors and/or matrix proteins (Zuk et al., 2001). Specific culture conditions w
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br Materials and methods br Results
2018-11-06
Materials and methods Results Discussion The present study showed that CBL treatment enhanced the survival of grafted NSCs in APP tg mice. In contrast, in the vehicle-treated group there was decreased survival of transplanted neuroblasts that was worse in the APP tg mice. This is consistent
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CD BMSCs formed heterotopic bone in vivo which
2018-11-06
CD34+ BMSCs formed heterotopic bone in vivo which corroborate their enrichment in osteoprogenitors. While in the present study, we employed CD34 as a marker that defines a specific lineage within BMSCs, it is plausible that CD34 plays a role in osteoblast differentiation. CD34 plays an important rol
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br Author contributions br Competing financial
2018-11-06
Author contributions Competing financial interests Acknowledgments We thank Dr. Sravan K. Goparaju for critical reading our manuscript. This work was supported in part by JSPS KAKENHI (23500446) and the iCeMS exploratory grant for junior investigators to KA. TI was supported in part by the
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Interestingly in contrast to the common
2018-11-06
Interestingly, in contrast to the common roles of SNAI-1 and 2 in repressing E-cadherin mediated EMT, SNAI-1 is the only SNAI factor that is expressed in endoderm and Hep cells, and that instructs positively hepatic cell fate. The unique function of SNAI-1 compared to SNAI-2 was also noted during th
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The host immune response has been
2018-11-06
The host immune response has been identified as a critical regulator of tumor development and progression (Dunn et al., 2004; Fridman et al., 2013; Hadrup et al., 2013). Several types of immune 17-aag participate in immunosurveillance by direct killing or production of cytokines. Our expression prof
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Sulfo-NHS-LC-Biotin Prolonged APs and EADs are typical of ph
2018-11-06
Prolonged APs and EADs are typical of pharmacologically induced LQTS modeled in nonhuman hearts (Shimizu and Antzelevitch, 2000; Studenik et al., 2001; Terentyev et al., 2014), yet few such studies examined [Ca2+]i transients. The lengthening of APs and [Ca2+]i transients after pharmacologically blo
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