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Recently using the cynomolgus macaque PGCs were first
2018-11-08
Recently using the cynomolgus macaque, PGCs were first identified in the amnion of the peri-implantation embryo at day 11 (Sasaki et al., 2016). The amnion develops coincident with the generation of the amniotic cavity and formation of the bilaminar embryo (Fig. 1, arrow points to amnion cells in th
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Human leukocyte class I HLA I molecules are critical for
2018-11-08
Human leukocyte class I (HLA-I) molecules are critical for antigen presentation to CD8+ cytotoxic T-lymphocyte (Garrido et al., 1993), and are understood to be widely expressed on the cell surface of all normal human tissues (Daar et al., 1984). However, HLA-I expression has been reported to be abse
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br Experimental Procedures br Author
2018-11-08
Experimental Procedures Author Contributions Acknowledgments We are grateful to Y. Okada (Aichi Medical University) and T. Matsumoto (Ajinomoto) for technical assistance, helpful advice, and discussions; T. Abe (Keio University) for statistical analysis; and all members of the H.O. laborato
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br Introduction Cardiac and skeletal myogenesis both generat
2018-11-08
Introduction Cardiac and skeletal myogenesis both generate striated muscle, but are traditionally thought of as two separate processes with distinct developmental anlagen. However, recent work suggests the existence of at least one bipotent anlage for cardiac and skeletal muscle: the common proge
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PD173074 br Results and Discussion br Experimental Procedure
2018-11-08
Results and Discussion Experimental Procedures Author Contributions Acknowledgments We would like to thank Hospital de São João for bone marrow samples and buffy coats. This work had the financial support of FCT/MEC through National Funds and, when applicable, co-financed by the FEDER th
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Our data have additional implications of applied
2018-11-08
Our data have additional implications of applied nature. Prospective isolation of putative “MSCs” from different tissues, based on the use of the minimal effective surface phenotype CD34−/CD45−/CD146+ (Sacchetti et al., 2007), leads to isolation of committed tissue-specific progenitors, not of broad
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The experimental design of this model provides
2018-11-08
The experimental design of this model provides several differences to standard 2D culture: EHTs are anchored between two flexible silicone posts, which generate a preload, and EHTs perform auxotonic contractile work (the physiological form of cardiac contraction) against elastic posts. This results
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Each method of KNO production has its
2018-11-07
Each method of KNO3 production has its advantages and disadvantages and the choice of one method over another is influenced by the availability of raw materials, purity of KNO3, waste treatment and cost of production (Jurišová et al., 2013). In Freilich (2005) it was reported that sodium chloride is
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hydralazine hcl Average hours of sleep per day was h consist
2018-11-07
Average hours of sleep per day was 7.9±1.7h, consistent with the suggestion of the US National Sleep Foundation (between 7 and 9h) and what has been reported in Latin America in 1776 individuals from 18 to 70 years of age from three of the largest cities where an average of 5.8h of sleep per day was
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Para el segundo juego mixto obtuvimos
2018-11-07
Para el segundo juego mixto obtuvimos que el promedio del bando con memoria 5 fue de -259.733 en el tiempo 8,192 de la simulación, mientras que la del bando con memoria 7 fue de -550.244, lo cual se puede apreciar en la gráfica 15. De acuerdo caspase pathway esto, y como se puede apreciar en la gráf
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En este n mero de
2018-11-07
En este número de se presentan temas de relevancia para nuestra economía. Se bordan desde distintas perspectivas para mostrar una serie de aspectos que inceden en su marcha. En el primer artículo se presenta un análisis econométrico por parte de Manuel Ontiveros sobre la determinación del sobrepeso
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Progress toward the treatment of three major parasitic
2018-11-07
Progress toward the treatment of three major parasitic diseases (sleeping sickness, Chagas disease, and leishmaniasis) was recently demonstrated in an article published online last month in the journal (August 8, 2016). Collectively, these three diseases affect 20 million people per year, resulting
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scd1 One thing that we learned in
2018-11-07
One thing that we learned in the presented ZIKV vaccine studies is that the yield of production of the ZIKV envelope E subunit protein was very low in the current format. This finding, also confirmed by a recently published ZIKV vaccine study (Larocca et al., 2016), is similar to what was previously
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The vast majority of malaria infections in low endemic
2018-11-07
The vast majority of malaria infections in low endemic settings are of low density (Imwong et al., 2016) but can contribute considerably to onward malaria transmission (Slater et al., 2015). However, the impact of current ACT and ACT-PQ on preventing onward malaria transmission from these low-densit
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The cross talk among adipose tissue
2018-11-07
The cross-talk among adipose tissue, insulin resistance, systemic order PalMitoyl Tripeptide-1 and intestinal microbiota is of crucial importance for illustrating the underlying mechanisms of obesity-related diseases. Previous studies have indicated that HFD-induced low-grade inflammation, obesity
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