• The patient was consented to treatment on clinical

  2019-06-13

  

  The patient was consented to treatment on clinical trial NCT02527447 and received treatment with salvage chemotherapy of mitoxantrone 12mg/m2/day IV on days 1–3, etoposide 200mg/m2/day continuous IV infusion (CIV) on days 8–10, and cytarabine 500mg/m2/day CIV on days 1–3 and 8–10 (EMA). Infectious p

• Air pollution also has a substantial effect on

  2019-06-13

  

  Air pollution also has a substantial effect on the wellbeing of people worldwide. This pollution can consist of sulfur dioxide, ozone, nitrogen dioxide, and fine-particulate ubiquitin conjugating enzyme of less than 2·5 μm in diameter (PM). 92% of the global population is exposed to higher-than-rec

• Findings children from households were enrolled either at ba

  2019-06-13

  

  Findings 5254 children from 3376 households were enrolled either at baseline or during the trial period. Mean 20-h kitchen concentration of PM2.5was reduced from 1386 μg/m3 to 930 μg/m3 There was a strong secular decline in the incidence of ALRI over the period of the study. The intervention was ass

• Splicing machinery dysfunctions have been

  2019-06-12

  

  Splicing machinery dysfunctions have been associated to CLL, in particular gene mutations (splicing factor 3B subunit 1) which are present in about 15% of patients . To our knowledge, no gene mutation has ever been detected in CLL. In order to broaden our knowledge on the frequency of splicing mutat

• Brugada syndrome BS is a hereditary arrhythmogenic disease

  2019-06-12

  

  Brugada syndrome (BS) is a hereditary arrhythmogenic disease characterized by a coved- or saddleback-type ST elevation in the right precordial lead on a 12-lead electrocardiogram (ECG) and ventricular fibrillation (VF) occurring mainly at night. During the past 2 decades, since Brugada and Brugada

• br Case report The patient

  2019-06-12

  

  Case report The patient was an 11-month-old boy. No abnormalities were observed throughout the embryonic stage and perinatal period. When he was 11 months and 10 day old, he suddenly developed pallor and poor responsiveness, with his eyes rolled back in his head, which continued for approximately

• Programmed death ligand PD L expression is a characteristic

  2019-06-12

  

  Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed

• La conclusi n principal que podemos extraer

  2019-06-12

  

  La conclusión principal que podemos extraer de la lectura de los discursos de los sujetos que conforman organizaciones sociales urbanas contemporáneas de Argentina y Uruguay, es que la integración regional se sostiene como una aspiración. Se trata de un proyecto que es considerado factible, pero que

• Pero adem s el ejemplo nos ilustra de c

  2019-06-12

  

  Pero, además, el ejemplo nos ilustra de cómo el sermón pastoral peruano no ahorra al indígena ninguno de los aspectos complejos del dogma. Pareciera que, en lo relativo pkd kinase este punto, no importara ya aquel requisito del decoro retórico sensibilizado hacia la capacidad de su receptor. Al cont

• Desde mediados de la d cada de los sesenta

  2019-06-12

  

  Desde mediados de la década de los sesenta, la embajada argentina pedía informes sobre las actividades políticas en general y sobre las consideradas subversivas en Guatemala. A juicio de la embajada, en 1978 no se podía analizar la “ola de violencia” en Guatemala sin incluirla en el contexto de lo q

• Esta propuesta est tica y argumental busca menos que

  2019-06-12

  

  Esta propuesta estética y argumental busca menos que despertar el asco de las formas y valores de la clase media porteña, ilustrar el modo en que la sexualidad puede darse en las zonas más profundas del conurbado bonaerense. Y tal es así, que esas localidades son nombradas por los mismos personajes:

• Hasta el tercer acto cuando Licurgo se casa y

  2019-06-11

  

  Hasta el tercer acto, cuando Licurgo se casa y vuelve clofibrate la racionalidad, presenta al Rey una serie de leyes, quien, sin conocerlas, le pregunta si desea hacerlas públicas, pero, desde otra óptica, Licurgo responde: Son, pues, el Rey y el Reino quienes deben acordar las leyes, para evitar c

• br Commentary Recordings of the activation

  2019-06-11

  

  Commentary Recordings of the activation sequence from the CS during tachycardia are expected to help discriminate among atrial tachyarrhythmias [2]. During ongoing typical CCW AFL, most of the CS is activated from proximal to distal, because the CS musculature, by being continuous with the RA myo

• In this issue of the

  2019-06-11

  

  In this issue of the , Shoja et al characterize the antimicrobial susceptibility pattern, resistance mechanisms, and typing of carbapenem-resistant (CRAB) isolates obtained from burn patients from a single center in Iran. They found that the rate of CRAB was high (92.5%) among burn patients. The mo

• br Case report A year old female presented with

  2019-06-11

  

  Case report A 50-year-old female presented with splenomegaly (24 cm) and pancytopenia in Mar. 2014. A bone marrow biopsy revealed hypocellular marrow (1st dna staining of R-COP (Fig. 3). Further 5 cycles of cytotoxic therapy with standard dose R-CEOP (rituximab; cyclophosphamide; epirubicin; vin

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