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In this study we further investigated the involvement of CRF
2021-03-29
In this study, we further investigated the involvement of CRF1 and CRF2 receptors of the dPAG in the regulation of panic-related responses. For this, we used two animal models that associate escape behavior with panic attacks: the elevated T maze and the electrical stimulation of the dPAG (for a ful
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Where a a a and b b b are respectively
2021-03-29
Where a, a, a and b, b, b are respectively, repulsive friction constants and attraction friction constants. c represents the quadratic repulsive friction constant and P is critical pressure (bar). CPA equation of state CPA model is an EOS that simply combines a cubic EOS (SRK-EOS) and an associ
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Recent studies have shown that some CLC genes participate in
2021-03-29
Recent studies have shown that some CLC genes participate in plant salt tolerance and have speculated that they function by mediating Cl− transport across the tonoplast. For instance, AtCLCc, a vacuolar anion transporter, is shown to be involved in the regulation of stomatal movement and to contribu
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Although it remains an unsettled issue evidence favors that
2021-03-29
Although it remains an unsettled issue, evidence favors that the endothelin ETA Simeprevir receptor may play a more important pathological role. While both endothelin ETA and ETB receptors are found in most tissues, endothelin ETA receptor is the predominant receptor responsible for the vasoconstric
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br Materials and methods br Results To
2021-03-29
Materials and methods Results To investigate the effect of 17βE on cell proliferation in the human renal tubular epithelia, BrdU uptake was measured in HRTEC primary and 3D-HRTEC cultures, allowing determination of the DNA replication rate. Representative microphotographs show BrdU uptake in H
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In some of our studies
2021-03-29
In some of our studies we examined the occurrence of ERβ and SHBG and a possible colocalization between them. Fig. 5 shows that there is no big difference in the occurence of ERβ after short time (A) as well as long time (B) treatment with E2. We can find the receptor at the cell membrane as well as
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br Conflict of interest statement br References and recommen
2021-03-29
Conflict of interest statement References and recommended reading Papers of particular interest, published within the period of review, have been highlighted as: Acknowledgements We acknowledge financial support by the Swiss State Secretariat for Education, Research and Innovation (Federal
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The imbalance that renders greater lipid
2021-03-29
The imbalance that renders greater lipid uptake toxic is unclear, but the comparison of our in vitro studies with those in mice illustrates the importance of TAG storage versus accumulation of less non-polar molecules. Protective effects of ACSL1 and PPARγ have been reported in other cell types. Par
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br Assessing DUB activity The Ub field has benefited
2021-03-27
Assessing DUB activity The Ub field has benefited greatly from the past efforts of biochemists and chemical biologists who have reconstituted Ub signals in vitro and generated tools for capturing or measuring DUB activities, many of which can be readily produced or are commercially available (Ekk
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The Lysine mutant is located in the tail region
2021-03-27
The Lysine429 mutant is located in the tail region of 5-HT2A, which is predicted to be unstructured. This region has been shown to interact, in vitro, with PSD95 and leads to differences in signaling (Xia et al., 2003). The ASK motif, a component of the tail region, is also important for regulation
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DHODH activity has been traditionally measured with the stan
2021-03-27
DHODH activity has been traditionally measured with the standard colorimetric assay that monitors 2,6-dichloroindophenol (DCIP) reduction as absorbance decrease at 600 nm . This assay has permitted the identification of several families of DHODH inhibitors in a successful high-throughput screening (
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Studies have shown that the cultivation of BMSCs
2021-03-27
Studies have shown that the cultivation of BMSCs under hypoxic conditions, treating with cytokines (such as HGF, IGF-1 and IL-6) and viral-mediated CXCR-4 gene delivery have been shown to re-establish CXCR-4 expression on the surface of stem Fluticasone propionate australia (Liu et al., 2010, Liu et
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br Alcohol and the amygdala br Alcohol
2021-03-27
Alcohol and the amygdala Alcohol and the CRF1 system Given the marked effects of alcohol on inhibitory neurotransmission in the amygdala and the regulation of amygdalar GABAergic activity by CRF and activity at the CRF1 receptor, the CRF system is a logical site for the actions of alcohol in t
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On close inspection the pattern
2021-03-27
On close inspection, the pattern shows large areas of very low point intensity where hardly any trees can be found. Anecdotal knowledge reveals that these regions are covered by a swamp, where the tree species is known to be very unlikely to grow, independent of local soil covariates and topography.
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The aim of the present study was to investigate
2021-03-27
The aim of the present study was to investigate the acute effects of THC on resting state Sweroside neurophysiology, and to examine the impact of COMT genotype on these effects. Thirty-nine healthy volunteers participated in a randomised, placebo-controlled, crossover pharmacological MRI study. Acu
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