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Given that A cells we used are not
2018-10-30
Given that A549 order (±)-Nutlin-3 we used are not derived from the small airways but are a transformed cell line with a pneumocyte phenotype, and our BMPR2 protein and mRNA expression work was performed in PBMCs but not lung tissue, we performed eQTL look-up in lung cell types (including whole hum
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vx-222 br Materials and Methods br Results br
2018-10-30
Materials and Methods Results Discussion Understanding the biology of human DC surface receptors and the functional consequences of the actions of individual receptors is fundamental for the rational design of medicines for cancers, inflammatory diseases (including autoimmune diseases) and
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br Materials and Methods DEFI is a French
2018-10-30
Materials and Methods DEFI is a French national study set up in 2004 to collect clinical data and biological specimens from adult patients with primary hypogammaglobulinaemia (Oksenhendler et al., 2008). The inclusion criteria in the DEFI study were adult patients with primary hypogammaglobulinae
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ARMS KIDINS carriers showed a
2018-10-30
ARMS/KIDINS220 carriers showed a picture consistent with low borderline intelligence and diminishing education and employment over earlier ages are inferred, since each completed at least one year of college (excluding dual-hit cases). While they showed the second slowest processing speeds after the
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Accumulating pre clinical and clinical evidence suggest that
2018-10-30
Accumulating pre-clinical and clinical evidence suggest that β-adrenergic receptor blockade may prove useful in the treatment of angiosarcoma. Chisholm et al. first reported detectable GSK1070916 of adrenergic receptors in vascular tumors (Chisholm et al., 2012). This finding was then confirmed by
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It is unlikely that overexpression of Ag
2018-10-30
It is unlikely that overexpression of Ag85A and/or Ag85B was responsible for the VZV reactivations, as extensive pre-clinical and clinical use of these PJ 34 in other experimental TB vaccines has been completed without reports of zoster. Overexpression of the Rv3407 antigen has not been previously
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topirimate Enteric bacteria have been implicated in cancer p
2018-10-30
Enteric bacteria have been implicated in cancer progression of the gut (Louis et al., 2014; Schwabe and Jobin, 2013). Their increased abundance in bile duct tissues could promote tumorigenesis in a similar manner. Indeed, the data in this study supports an increase in the microbial production of car
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To measure the presence of
2018-10-30
To measure the presence of a wide range of pathogens directly from blood samples we leveraged a recently developed engineered version of the natural human blood opsonin, Mannose Binding Lectin, as a broad-spectrum agent that can capture a wide range of pathogens and released toxins. This engineered
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br Experimental design materials and methods br
2018-10-29
2. Experimental design, materials and methods Acknowledgments This work was supported by operating grants from the Canadian Institutes of Health Research (CIHR-27R18706). B.B.F. is the University of British Columbia Peter Wall Distinguished Professor. No competing interests exist for this work
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br Acknowledgements Thank you to the people the lovely
2018-10-29
Acknowledgements Thank you to the people the lovely people in the San Polino winery, who generously opened their doors and helped us collect the samples and strains needed to produce these data. We especially thank Katia Nussbaum, Luigi Fabbro, Alberto Gjilaska, and Daniel Fabbro. We also thank B
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br Experimental design materials and methods The experiment
2018-10-29
2. Experimental design, materials and methods The experiment was conducted at a rice field with long and short duration variety of BPT5204 (150 days) and IR64 (90–120 days), which normally yields 5.5 to 6.5t/ha-1 and 4.0 to 4.5t/ha-1 in 2013–2014 at rice field of Alapakkam: Latitude: 11.3600°N an
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br Conclusions br Acknowledgements br Introduction
2018-10-29
Conclusions Acknowledgements Introduction Over the past few years the neural architecture of how cognitive control is supported when having to process emotional information has slowly begun to be uncovered (e.g., Cromheeke and Mueller, 2014; Dolcos and McCarthy, 2006; Kanske and Kotz, 2011;
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Una de las consecuencias m s relevantes de que salgan
2018-10-29
Una de las consecuencias más relevantes de que salgan XMU-MP-1 la luz las memorias es que los hermafroditas también conquistan un escaño en la escritura. Del recuento de los daños de Herculine editados por Tardieu se desprenden la mencionada novela corta Un caso escandaloso, de Oscar Panizza, y la n
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br Simulation results and discussion
2018-10-29
Simulation results and discussion Conclusions This study used the intelligent software called DesignBuilder, which employs the powerful and comprehensive nf-κb pathway simulation engine EnergyPlus, to simulate indoor thermal comfort and energy issues. Three scenarios of the indoor environment
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br Conservation treatment br Local simulation and recovery
2018-10-29
Conservation treatment Local simulation and recovery The colored painting in Xiaonan Garden has been severely destroyed. For the lost part, we use an infrared camera to obtain an infrared photo but find no damage. Thus, we conduct a typological analysis of the colored painting. Based on simila
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